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Endocrine Abstracts

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ea0020p444 | Obesity and Metabolism | ECE2009

Letrozole normalizes serum testosterone and reduces body weight in morbidly obese men with obesity-related hypogonadotropic hypogonadism

Loves Sandra , de Jong Jos , van Sorge Adriaan , Telting Darryl , de Boer Hans

Introduction: Hypogonadotropic hypogonadism is frequently observed in morbidly obese men, due to aromatase-dependent conversion of androgens to estrogens in adipocytes. The clinical impact of this sex hormone imbalance is not known.Aim: To evaluate the clinical effects of aromatase inhibition in obesity-related hypogonadotropic hypogonadism.Methods: Double-blind, placebo-controlled trial for 6 months in severely obese men (BMI &#62...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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